Endocytic accessory protein
WebAug 30, 2007 · AP-2 is a key regulator of the endocytic protein machinery driving clathrin-coated vesicle (CCV) formation. One critical function, mediated primarily by the AP-2 α-ear, is the recruitment of accessory proteins. NECAPs are α-ear-binding proteins that enrich on CCVs. Here, we have solved the structure of the conserved N-terminal region of … WebOct 11, 2024 · It clusters at PI(4,5)P 2-rich regions of the plasma membrane, and binds cargo proteins, numerous endocytic accessory proteins and clathrin (Traub, 2009; Kelly and Owen, 2011). The μ2 subunit of AP2 binds GluA2 and GluA3 subunits directly (Figure 1C ), and this interaction is required for hippocampal LTD but not constitutive AMPAR …
Endocytic accessory protein
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WebAug 10, 2004 · Mnb/Dyrk1A is a proline-directed serine/threonine kinase implicated in Down's syndrome. Mnb/Dyrk1A was shown to phosphorylate dynamin 1 and alter its … WebOct 1, 2001 · Organelles in the endocytic pathway are composed of a mosaic of structural and functional regions. These regions consist, at least in part, of specialized protein–lipid domains within the plane ...
WebApr 30, 2024 · Numerous endocytic accessory proteins (EAPs), which modulate various aspects of CCP assembly and maturation, contribute to the formation of clathrin-coated vesicles (CCVs) that transport cargo to the cell interior. However, the exact functions of many of these EAPs are still poorly understood, ... WebDec 15, 2024 · This highly regulated process involves a myriad of endocytic accessory proteins (EAPs), many of which are multidomain proteins that encode a wide range of …
WebIn addition to the major coat proteins, clathrin triskelia and adaptor protein complexes, CME requires a myriad of endocytic accessory proteins and phosphatidylinositol … WebJul 7, 2009 · Here, we use this assay to identify the differential effects of siRNA-repressed expression levels of 10 endocytic accessory proteins: SNX9, epsin1, Hip1R, Eps15, …
Webmyriad of endocytic accessory proteins (EAPs). These EAPs, many of which are multidomain proteins, encode multiple bio-chemical activities, including curvature …
WebOct 1, 2003 · Endocytosis by clathrin-coated vesicles (CCVs) is an important mechanism mediating protein internalization. Here, we show that two proteins identified through a proteomics analysis of CCVs are new co... bleach filler episodes guidebleach filelrsWebNov 1, 2016 · The crowding effect in particular has received considerable attention recently, in part because it is a colligative mechanism—implying that it could, in principle, be explored by any peripheral protein. Here we sought to clarify to what extent this mechanism is exploited by endocytic accessory proteins. frank rally postWebOct 3, 2014 · DOI: 10.1101/cshperspect.a016733 Abstract Up to 60 different proteins are recruited to the site of clathrin-mediated endocytosis in an ordered sequence. These … frank raising hopeWebAs a central player in endocytosis and autophagy, TPC associates with a plethora of endocytic accessory proteins, cargo proteins, and autophagy-related proteins ( 8, … frank ramond cdWebCME occurs via the assembly and maturation of clathrin-coated pits that concentrate cargo as they invaginate and pinch off to form clathrin-coated vesicles. In addition to the major … frank ramos facebookWebMay 20, 2009 · Here, we use this assay to identify the differential effects of siRNA-repressed expression levels of 10 endocytic accessory proteins: SNX9, epsin1, Hip1R, Eps15, … bleach filler arcs worth watching