WebGambogic acid C38H44O8 CID 5353639 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, … WebNov 15, 2007 · Gambogic acid (GA), a xanthone derived from the resin of the Garcinia hanburyi, has been recently demonstrated to bind transferrin receptor and exhibit potential anticancer effects through a signaling mechanism that is not fully understood.Because of the critical role of NF-κB signaling pathway, we investigated the effects of GA on NF …
GAMBOGE - Uses, Side Effects, and More - WebMD
WebJul 3, 2024 · Gambogic acid, a common traditional Chinese medicine and widely distributed throughout South China, Vietnam, Cambodia, and Thailand. It is prenylated xanthone which is the significant bioactive... WebJan 10, 2024 · Gambogic acid is derived from the gamboges resin of the tree Garcinia hanburyi. Gambogic acid inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50s of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM. Properties Articles 29 Spectrum Names Gambogic Acid Biological Activity Chemical & Physical Properties MSDS christmas clip art-free bells
Gambogic Acid Autophagy BCL TargetMol
WebGambogic acid is an apoptosis inducer in several tumor cell lines including T47D cells. Activates caspases (EC 50 values are 0.78 - 1.64 μM) and competitively inhibits antiapoptotic Bcl-2 family proteins (IC 50 values are 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μM for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 respectively). WebGambogic amide specifically interacts with the cytoplasmic jux-tamembrane domain of TrkA receptor and triggers its dimerization. … WebSep 1, 2024 · The molar mass of neogambogic acid is 646.77 g·mol−1 and its molecular formula is C38H46O9. It appears as yellow crystalline, since it’s in large amount in the original ingredients, the extraction process is simple and low-cost, showing significant value of research and develop- ment [3]. christmas clip art-free border